Interrogatives
er...umh....[cough]...[hack; hack]....do, re, mi, fa, sol...
Now that I have my voice where I want it:
The reader has to read the story and feel like the protag is speaking using their thought patterns.
The first writer these words conjure up is Stephen R. Donaldson, followed closely by China Mieville, both of whom strike me as totally unconcerned whether or not us readers feel as if their protagonistas are speaking using our thought patterns. I cannot read either one without a dictionary very close. However, that may support your thesis as I have stopped reading both.

Writing is not a thing where you try to impress the reader with your prose. OTOH, it is also not a thing where you wish to unimpress your reader with your prose. Back in my critting days, this was always the point that hung me up: incomprehensible prose. Not gibberish, not stylishness, but total unconcern with the logic of the verbiage, e.g., watching a building fire in a mountain 500 miles away.

You need to dream up the 100 and 1th 'great idea' or possibly the 200 and 2th 'great idea'. Can you expand on this one a bit more? Say I want to write a story about a youth raised by aliens who returns to her own society and recognizes she is now the change agent for that society. How many times has that been done? Can it not be done again? How many times has "the best laid plans of mice and men" been done? Can it not be done again? I think what you are driving at is the need to dream up your own hook, your own slant on the story, your own voice when it comes to the topic. Is that fair?